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Variables
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Total
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Male
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Female
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|---|
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HOMA-β (%)
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HOMA-IR
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HOMA-β (%)
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HOMA-IR
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HOMA-β (%)
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HOMA-IR
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|---|
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Coefficient (95% C.I)
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p value
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Coefficient (95% C.I)
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p value
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Coefficient (95% C.I)
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p value
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Coefficient (95% C.I)
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p value
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Coefficient (95% C.I)
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p-value
|
Coefficient (95% C.I)
|
p value
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|---|
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Urine arsenobetaine (μg/g_cr)
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|
1st quartile (Undetectable-16.36)
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Reference
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Reference
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Reference
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Reference
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Reference
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Reference
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2nd quartile (16.91–70.70)
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−9.613 (−24.490, 5.264)
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0.205
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−0.208(−0.449, 0.033)
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0.091
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−30.043(−53.954, −6.133)
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<0.05
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−0.405(−0.835, −0.025)
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0.065
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5.394(−13.276, 24.064)
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0.571
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−0.059(−0.329, 0.211)
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0.668
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3rd quartile (71.57–321.71)
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−17.796(−33.257, −2.334)
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<0.05
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−0.219(−0.469, 0.031)
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0.086
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−22.382(−44.023, −0.742)
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<0.05
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−0.343(−0.732, 0.046)
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0.084
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−12.575(−35.104, 9.954)
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0.274
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−0.071(−0.397, 0.254)
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0.667
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4th quartile (324.19–2620.78)
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−8.368(−24.891, 8.056)
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0.318
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−0.038(−0.304,0.228)
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0.779
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−14.950(−39.251, 9.351)
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0.228
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−0.027(−0.464, 0.410)
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0.902
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−3.857(−25.647, 17.932)
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0.729
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−0.055(−0.370, 0.259)
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0.731
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Age (years)
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01.117(−1.486,0.748)
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<0.001
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−0.004(−0.010, 0.002)
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0.172
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−1.211(−1.752, −0.671)
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<0.001
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−0.006(−0.015, 0.004)
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0.258
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−1.052(−1.558, −0.546)
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<0.001
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−0.003(−0.011, 0.004)
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0.376
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BMI (kg/cm2)
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5.188 (3.523, 6.853)
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<0.001
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0.136 (0.109, 0.163)
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<0.001
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5.465 (3.075,7.855)
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<0.001
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0.149 (0.106, 0.192)
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<0.001
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5.565 (3.184, 7.946)
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<0.001
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0.132 (0.097, 0.166)
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<0.001
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Smokinga
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−10.452(−22.42, 1.515)
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0.087
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−0.114(−0.308, 0.080)
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0.248
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−11.827(−27.403,3.750)
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0.137
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−0.251(−0.531, 0.029)
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0.079
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8.524 (−14.362, 31.410)
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0.465
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0.242(−0.088, 0.572)
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0.151
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Alcohol consumptionb
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−14.864(−26.291, −3.436)
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<0.05
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0.065(−0.120, 0.250)
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0.492
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−18.557(−37.121, 0.006)
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0.050
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0.077(−0.256, 0.411)
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0.650
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−9.699(−24.618, 5.219)
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0.203
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0.045(−0.170, 0.261)
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0.680
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Regular exercisec
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−4.067(−15.791, 7.657)
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0.497
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−0.137(−0.327, 0.053)
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0.157
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−2.490(−18.472, 13.492)
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0.760
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−0.031(−0.318, 0.256)
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0.833
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−4.731(−21.725, 12.264)
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0.585
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−0.260(−0.505, −0.015)
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<0.05
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Blood mercury (μg/L)
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|
1st quartile (1.188–2.977)
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Reference
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Reference
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Reference
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Reference
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Reference
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Reference
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2nd quartile (2.987–4.598)
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15.686 (1.036,30.337)
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<0.05
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−0.046(−0.283, 0.191)
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0.705
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−0.415(−25.210, 24.381)
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0.974
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−0.264(−0.710, 0.182)
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0.246
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27.067 (8.938, 45.197)
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<0.01
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0.108(−0.153, 0.370)
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0.417
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3rd quartile (4.625–6.969)
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5.642(−10.252, 21.536)
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0.487
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0.023(−0.235, 0.280)
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0.862
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−2.752(−27.702, 22.197)
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0.829
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−0.388(−0.836, 0.061)
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0.090
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11.404(−9.568, 32.377)
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0.287
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0.304 (0.001, 0.607)
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<0.05
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4th quartile (6.997–37.654)
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−15.172(−32.179, 1.835)
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0.08
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−0.165(−0.440, 0.110)
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0.240
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−27.387(−52.474, −2.300)
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<0.05
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−0.524(−0.975, −0.073)
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<0.05
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3.667(−21.177, 28.512)
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0.772
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0.178(−0.181, 0.536)
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0.332
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Abbreviations: BMI body mass index, C.I confidence interval
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aSmoking status was indicated as ‘yes’ for participants who had smoked more than five packs of cigarettes during their life and were currently smoking
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bAlcohol consumption was indicated as ‘yes’ for participants who consumed at least one glass of alcohol every month over the previous year
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cRegular exercise was indicated as ‘yes’ when the participant performed mederate or strenuous exercise on a regular basis (for more than 30 min at a time and more than five times per week in the case of moderate exercise; for more than 20 min at a time in the case of strenuous exercise)
