Table 2 Genetic susceptibility in subjects with high radon concentration
From: Gene mutation discovery research of non-smoking lung cancer patients due to indoor radon exposure
| Author/year | Region | Subjects | Gene |
|---|---|---|---|
| Sinitsky MY et al. 2015 [39] | Russia | children | ADPRT, hOGG1, NBS1, XRCC1, XpC, XpD, XpG |
| Ruano-Ravina A et al. 2014 [40] | Spain | 792 lung cancer | GSTM1,GSTT1 |
| Bonner MR et al. 2006 [41] | US | 270 lung cancer | GSTM1 |
| Druzhinin VG et al. 2011 [44] | Russia | healthy voluteers | hOGG1, ADPRT, APE1, XRCC1, XpG, XpC, XpD, NBS1 |
| Kiuru A et al. 2005 [45] | Finland | 84 healthy nonsmokers | OGG1, XPD, XRCC1, XRCC3 |
| Yngveson A et al. 1999 [46] | Sweden | 83 nonsmoking lung cancer | p53 |
| 250 smoking lung cancer | |||
| Hayes VM et al. 1996 [47] | South Africa | SCLC | TP53 |
| Takeshima Y et al. 1996 [48] | Japan | 28 adenocarcinomas non smoking female | p16/CDKN2, p53 |
| Leng S et al. 2013 [49] | USA | 267 SCC case | SIRT1 |
| 383 control | |||
| Leng S et al. 2015 [50] | USA | 242 SCC | IL-6 |
| 336 control |